10 Ozone Therapy Benefits and Side Effects: What You Need to Know
- Dr. Collins

- 7 days ago
- 5 min read
Ozone therapy has garnered increasing attention in integrative and regenerative medicine for its potential to restore cellular health, enhance circulation, and support the body’s natural healing processes. At Proactive Choice in Bend, Oregon, this innovative therapy is utilized as part of a comprehensive holistic approach to wellness, targeting chronic inflammation, detoxification, and cellular rejuvenation.
But what exactly does ozone therapy do, and how does it benefit your health? Let’s explore the top 10 benefits and the possible side effects you should be aware of before considering this cutting-edge treatment.
Top 10 Ozone Therapy Benefits and Side Effects Explained
What Is Ozone Therapy?
Ozone therapy utilizes a medical-grade form of ozone gas—a molecule composed of three oxygen atoms (O₃)—to stimulate healing and promote detoxification. When administered properly under medical supervision, ozone can enhance oxygen utilization in the body, boost immune responses, and promote tissue repair.
There are multiple methods of administration, including intravenous (IV) ozone therapy, insufflation, and topical applications, depending on the patient’s needs and condition being treated.

10 Major Benefits of Ozone Therapy
1. Enhances Oxygen Utilization
Ozone therapy helps the body utilize oxygen more efficiently by enhancing the flexibility of red blood cells and improving circulation. This process enhances oxygen delivery to tissues—particularly beneficial for athletes, individuals with chronic fatigue, or those recovering from illness or injury.
2. Boosts Immune Function
Ozone can stimulate white blood cell activity, strengthening the immune system’s ability to fight infections, viruses, and autoimmune imbalances. Many patients report fewer colds, faster recovery from illness, and improved overall resilience after consistent treatments.
3. Reduces Chronic Inflammation
Chronic inflammation lies at the root of most degenerative diseases. Ozone therapy helps modulate inflammatory pathways, reducing pain and swelling while promoting faster tissue healing — a key advantage for individuals with arthritis, fibromyalgia, or autoimmune conditions.
4. Supports Detoxification
Ozone activates antioxidant enzymes and helps break down toxins stored in fat and tissue. By improving liver function and circulation, it enhances the body’s ability to eliminate heavy metals, environmental pollutants, and metabolic waste, making it an excellent complement to chelation or other detoxification programs.
5. Improves Circulation and Heart Health
By promoting the production of nitric oxide and improving the oxygen-carrying capacity of blood, ozone therapy supports cardiovascular health. Better circulation means improved energy, sharper cognition, and stronger overall vitality — especially for individuals with poor peripheral circulation or those at risk for heart disease.
6. Accelerates Wound and Tissue Healing
Ozone increases the availability of growth factors and oxygen in damaged tissues, stimulating faster repair. It’s often used in regenerative medicine for sports injuries, post-surgical recovery, diabetic ulcers, and the management of joint pain.
7. Fights Bacterial, Viral, and Fungal Infections
Ozone’s antimicrobial properties make it effective against a wide range of pathogens, including bacteria, viruses, and fungi. This is why it’s often used as an adjunctive therapy for chronic infections, such as Lyme disease, Epstein-Barr virus, or mold-related illnesses.
8. Enhances Mitochondrial Function
At the cellular level, ozone stimulates mitochondria — the “power plants” of your cells — to produce more energy (ATP). This can lead to increased mental clarity, enhanced physical stamina, and improved overall well-being. For those experiencing chronic fatigue or metabolic sluggishness, ozone therapy can be a game-changer.
9. Promotes Longevity and Anti-Aging
Because it enhances oxygenation, reduces oxidative stress, and supports detoxification, ozone therapy is increasingly recognized for its potential to promote anti-aging. Many patients notice improvements in skin tone, energy, cognitive sharpness, and mood — all hallmarks of youthful vitality.
10. Complements Other Holistic Therapies
Ozone therapy integrates seamlessly with other naturopathic and regenerative treatments such as IV nutrition, hormone optimization, and chelation therapy. When combined under expert medical supervision, these modalities enhance each other’s effects for deeper, longer-lasting results.
You May Like: 10 Benefits Of Ozone Therapy Treatments
Possible Side Effects of Ozone Therapy
While ozone therapy is generally safe when performed by a trained medical professional, some individuals may experience mild, temporary side effects as the body adjusts to treatment. These may include:
Fatigue or lightheadedness immediately after treatment due to detoxification.
Mild headache or nausea as the body releases stored toxins.
Temporary irritation or inflammation at the injection or infusion site.
Herxheimer reaction (detox response)—a short-term symptom flare-up as pathogens and toxins are eliminated.
These effects are typically short-lived and can be minimized through proper hydration, rest, and supervision from an experienced practitioner. At Proactive Choice, all ozone therapies are carefully monitored to ensure comfort and safety throughout the process.
Is Ozone Therapy Right for You?
Ozone therapy is ideal for individuals seeking natural ways to improve circulation, reduce inflammation, and support their body’s healing and detox pathways. It’s especially beneficial for:
Athletes looking to enhance recovery and performance
People with chronic fatigue, brain fog, or autoimmune conditions
Individuals recovering from surgery or infection
Those exploring holistic anti-aging and wellness programs
A thorough medical evaluation ensures that ozone therapy is tailored to your specific health goals and integrated safely into your overall care plan.
Conclusion
Ozone therapy offers a remarkable combination of detoxification, oxygenation, and regeneration benefits—all aimed at restoring balance, vitality, and long-term health. When administered under expert medical guidance, it becomes a powerful ally in your journey toward wellness and longevity.
At Proactive Choice in Bend, Oregon, Dr. Drew Collins and his team provide evidence-based ozone and regenerative therapies designed to help you perform, recover, and feel your best—naturally and safely.
Take the first step toward renewed energy and optimal health. Call (858) 333-5196 today to schedule your consultation and discover how ozone therapy can help you live stronger, longer, and better.
Want to consult a holistic medical practitioner in Oregon? Please take a look at the links below.
FAQs on 10 Ozone Therapy Benefits and Side Effects
What is ozone therapy and how does it work?
Ozone therapy is a medical treatment that uses a form of oxygen called ozone (O3) to promote healing. It works by inducing controlled oxidative stress, which stimulates the body’s antioxidant defenses, improves oxygen metabolism, enhances immune response, and reduces inflammation.
What are the top benefits of ozone therapy?
The main benefits include boosting the immune system, reducing inflammation, improving blood circulation, helping wound healing, relieving pain, supporting chronic infection management, and enhancing quality of life in conditions like arthritis, fibromyalgia, and certain cardiovascular diseases.
Can ozone therapy help with chronic pain conditions?
Yes, ozone therapy has shown efficacy in alleviating chronic pain from conditions such as osteoarthritis, fibromyalgia, and chronic back pain by reducing inflammation and improving tissue oxygenation.
Is ozone therapy effective for improving immune function?
Ozone therapy activates immune cells and stimulates immune responses, which can help the body fight infections, reduce inflammation, and support autoimmune conditions.
What are the potential side effects of ozone therapy?
Side effects are generally mild but can include irritation at the injection site, temporary fatigue, or mild respiratory symptoms if ozone gas is inhaled. Serious adverse effects are rare when administered correctly by trained professionals.
Is ozone therapy safe for cancer patients?
Ozone therapy may be used as an adjunctive treatment in oncology to improve oxygenation, reduce treatment side effects like nausea and fatigue, and support immune function. However, it is not a standalone cancer cure and should be used under medical supervision.
How is ozone therapy administered?
Common administration routes include intravenous autohemotherapy (mixing ozone with blood), injections into joints or muscles, and topical applications for wounds. The method depends on the condition being treated.
Are there any conditions where ozone therapy should be avoided?
Ozone therapy is not recommended for pregnant women, patients with thyroid or blood clotting disorders, and those with certain respiratory problems. Proper assessment by a healthcare provider is essential before starting treatment.
How long does it take to see results from ozone therapy?
Results vary based on the condition and treatment method; some patients experience relief after a few sessions, while chronic conditions may require ongoing treatment over several weeks or months.
Can ozone therapy cause oxidative damage or worsen health conditions?
Ozone therapy induces a controlled oxidative stress that triggers protective antioxidant responses rather than causing harm. When performed correctly, it generally does not cause oxidative damage but supports cellular defense mechanisms.




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